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Articles

The impact of gene polymorphisms in angiotensin receptor 1 and aldosterone synthase in peritoneal dialysis patients

Trošt Rupnik A, Kovač D, Pajek J, Osredkar J, Marc J, Lindič J

8 June 2017

Category:

Nephrology And Internal Medicine

Doi:

Abstract

Aim: Longevity of peritoneal membrane is an important issue in patients treated with peritoneal dialysis (PD). In our study, we studied the impact of angiotensin receptor 1 (AGT R1) and aldosterone syn- thase (CYP11B2) gene polymorphism on peritoneal concentrations of interleukin-6 (PI-IL-6), vascul ...

Effects of an Ad Libitum Consumed Low-Fat Plant-Based Diet Supplemented with Plant-Based Meal Replacements on Body Composition Indices

Jakše B, Pinter S, Jakše B, Bučar Pajek M, Pajek J

27 March 2017

Category:

Nutrition

Doi:

Abstract

Objective. To document the effect of a diet free from animal-sourced nutrients on body composition indices. Methods. This was a nonrandomized interventional ()-control () trial with a 10-week, low-fat, plant-based diet supplemented with two daily meal replacements. The meals were allowed to be eaten ...

Characterization of deficits across the spectrum of motor abilities in dialysis patients and the impact of sarcopenic overweight and obesity

Bučar Pajek M, Pajek J.

14 March 2017

Category:

Physical Activity

Doi:

Abstract

Background & aims
Physical performance deficits in kidney failure predict mortality and quality of life. We aimed to quantify deficits in multiple motor abilities, investigate associations of lean and fat tissue content with test results and analyzed performance of sarcopenic individuals with adipos ...

Preoperative ultrasound still valuable for radio-cephalic arteriovenous fistula creation?

Pajek J, Malovrh M

5 March 2017

Category:

Nephrology And Internal Medicine

Doi:

Abstract

Radio-cephalic arteriovenous fistula is a prototype hemodialysis access with small incidences of infection and distal ischemia, it spares proximal veins for future access use and it helps in the maturation of veins that may be used for more proximal access creations. This access type is prone to hig ...

Tubular urinary indexes reliably distinguish between primary tubulointerstitial and primary glomerular diseases in patients referred for kidney biopsy

Škoberne A, Borštnar Š, Avguštin N, Kovač D, Rigler AA, Večerić-Haler Ž, Pajek J, Krsnik M, Kojc N, Ferluga D, Lindič J

31 December 2016

Category:

Nephrology And Internal Medicine

Doi:

Abstract

Aims: Kidney biopsy remains the gold standard for accurately diagnosing renal diseases. Urinalysis and assessment of renal function are the cornerstones for assessment of patients prior to biopsy. There is significant overlap in the results of routine urine parameters (proteinuria, erythrocyturia, l ...

The predictive value of urinary vascular endothelial growth factor (VEGF) on worsening kidney function in proteinuric chronic kidney disease

Avguštin N, Rotar Ž, Pajek J, Kovač D, Osredkar J, Lindič J

31 December 2016

Category:

Nephrology And Internal Medicine

Doi:

Abstract

Objectives: To evaluate the role of urinary vascular endothelial growth factor (VEGF) as an early predictor of chronic kidney disease (CKD) progression in patients with glomerular diseases. Methods: We prospectively included patients with proteinuria and CKD grade 1 – 5 due to glomerular disease at ...

Vascular Access Effects on Motor Performance and Anthropometric Indices of Upper Extremities

Bučar Pajek M, Čuk I, Pajek J

15 June 2016

Category:

Nephrology And Internal Medicine

Doi:

Abstract

A decrement of upper extremity motor performance is a concern with vascular access creation. We analyzed differences in handgrip strength, tapping test and anthropometric indices of arms with and without vascular access (N = 87) and compared them to bilateral differences in control subjects (N = 140 ...

Integrative Examination of Motor Abilities in Dialysis Patients and Selection of Tests for a Standardized Physical Function Assessment

Bučar Pajek M, Leskošek B, Vivoda T, Svilan K, Čuk I, Pajek J.

15 June 2016

Category:

Physical Activity

Doi:

Abstract

To reduce the need for a large number of executed physical function tests we examined inter‐relations and determined predictive power for daily physical activity of the following tests: 6‐min walk, 10 repetition sit‐to‐stand, time up‐and‐go, Storke balance, handgrip strength, upper limb tapping and ...

Six-Minute Walk Test in Renal Failure Patients: Representative Results, Performance Analysis and Perceived Dyspnea Predictors

Bučar Pajek M, Čuk I, Leskošek B, Mlinšek G, Buturović Ponikvar J, Pajek J.

15 March 2016

Category:

Physical Activity

Doi:

Abstract

Objectives
Six-minute walk test in dialysis population hasn’t been consistently evaluated for the isolated impact of renal failure and other predictive factors. We measured six-minute walk distance in patients representative for low level of comorbidity and searched for potentially modifiable predic ...

Isolated Effects of Renal Failure, Anthropometric Indices, and Serum Total Iron-Binding Capacity as Determinants of Muscle Performance in Hemodialysis Patients

Bučar Pajek M, Svilan K, Vivoda T, Škoberne A, Pajek J.

26 January 2016

Category:

Physical Activity

Doi:

Abstract

Objective: We quantified the isolated impact of end-stage renal disease (ESRD) on physical performance under contemporary hemodialysis treatment independent of comorbid diseases, characterized principal anthropometric components, and adjusted for their influence and compared associations of C-reacti ...

Overcoming the Underutilisation of Peritoneal Dialysis

Pajek J

10 November 2015

Category:

Nephrology And Internal Medicine

Doi:

Abstract

Peritoneal dialysis is troubled with declining utilisation as a form of renal replacement therapy in developed countries. We review key aspects of therapy evidenced to have a potential to increase its utilisation. The best evidence to repopulate PD programmes is provided for the positive impact of t ...

Glucocorticoids in nephrology I: pharmacology and side effects

Pajek J, Jensterle Sever M

4 May 2015

Category:

Nephrology And Internal Medicine

Doi:

Abstract

Glucocorticoids have been used in clinical medicine since 1940s. Despite the time-long use they are still a subject of active ongoing research. We describe the mode of action, pharmacology and side effects to enable proper prescription of these drugs. Glucocorticoids exert genomic and non-genomic ef ...

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