

Articles
Glucocorticoids in nephrology II: indications and dosage
Pajek J
30 April 2015
Category:
Nephrology And Internal Medicine
Doi:
Abstract
Present article describes glucocorticoid usage in nephrology and renal transplantation, the dosages in induction and maintenance treatment phases and discontinuation. Key evidence and landmark trials are referenced to establish the basis for modern glucocorticoid application in specific kidney disea ...
Non-inferiority of creatinine excretion rate to urinary L-FABP and NGAL as predictors of early renal allograft function
Pajek J, Škoberne A, Šosterič K, Adlešič B, Leskošek B, Bučar Pajek M, Osredkar J, Lindič J
15 July 2014
Category:
Nephrology And Internal Medicine
Doi:
Abstract
Background
We evaluated accuracy of urinary liver type fatty acid-binding protein (L-FABP) for prediction of early allograft function and compared it to neutrophil gelatinase associated lipocalin (NGAL), diuresis and urinary creatinine excretion rate (UCr).
Methods
Urine samples from 71 consecutive ...
Serum with phospholipase A2 receptor autoantibodies interferes with podocyte adhesion to collagen
Škoberne A, Behnert A, Teng B, Fritzler MJ, Schiffer L, Pajek J, Lindič J, Haller H, Schiffer M
17 June 2014
Category:
Nephrology And Internal Medicine
Doi:
Abstract
Background
The majority of sera from patients with primary membranous nephropathy have autoantibodies against the M‐type phospholipase A2 receptor (PLA2R) which is expressed on human podocytes. The rabbit variant of PLA2R attaches to collagen type IV via the fibronectin type II domain, which is also ...
Outcomes of peritoneal dialysis patients and switching to hemodialysis: a competing risks analysis
Pajek J, Hutchison AJ, Bhutani S, Brenchley PE, Hurst H, Perme MP, Summers AM, Vardhan A
30 April 2014
Category:
Nephrology And Internal Medicine
Doi:
Abstract
Background
We performed a review of a large incident peritoneal dialysis cohort to establish the impact of current practice and that of switching to hemodialysis.
Methods
Patients starting peritoneal dialysis between 2004 and 2010 were included and clinical data at start of dialysis recorded. Compe ...
Urinary Immunoglobulin G to Albumin Ratio and N-Acetyl-Beta-D-Glucosaminidase as Early Predictors of Therapeutic Response in ANCA-Associated Glomerulonephritis
Mravljak M, Vizjak A, Ferluga D, Pajek J, Kovac D, Skoberne A, Ales Rigler A, Kveder R, Kosir A, Lindic J
12 December 2013
Category:
Nephrology And Internal Medicine
Doi:
Abstract
Background
The aim of our study was to evaluate the prognostic value of glomerular and tubular proteinuria and tubular enzymuria as early indicators of therapeutic response to induction therapy with i.v. pulse cyclophosphamide (CyC) and methylprednisolone (MP) in patients with antineutrophil cytopl ...
Influence of renin-angiotensin-aldosterone system-blocking drugs on peritoneal membrane in peritoneal dialysis patients
Trošt Rupnik A, Pajek J, Guček A, Osredkar J, Kovač D, Bren A, Klančič D, Saksida S, Rus I, Globokar M, Drozg A, Lešnik M, Plešivčnik Z, Ekart R, Lopert S, Lindič J
10 August 2013
Category:
Nephrology And Internal Medicine
Doi:
Abstract
Therapy with renin‐angiotensin‐aldosterone system (RAAS)‐blocking drugs prevents the development of fibrosis and angiogenesis in animal models and humans. In our study we have evaluated the systemic effect of RAAS blockade and the effect on peritoneal growth factors, cytokine production and membrane ...
Successful treatment of severe hantavirus nephritis with corticosteroids: a case report and literature review
Martinuč Bergoč M, Lindič J, Kovač D, Ferluga D, Pajek J
10 August 2013
Category:
Nephrology And Internal Medicine
Doi:
Abstract
Hantaviruses can be associated with severe form of hemorrhagic fever with renal syndrome although there are only a few cases reporting chronic kidney disease after hantavirus infection. We report a severe nonresolving chronic renal failure after protracted Dobrava hantavirus infection successfully t ...
Is the quality of judging in women artistic gymnastics equivalent at major competitions of different levels?
Pajek Bučar M., Čuk I, Pajek J, Kovač M, Leskošek B.
4 July 2013
Category:
Physical Activity
Doi:
Abstract
In the present study, the reliability and validity of judging at the European championship in Berlin 2011 were analysed and the results were compared to a different level gymnastic competition – Universiade 2009 in Belgrade. For reliability and consistency assessment, mean absolute judge deviation f ...
Low back pain in physically active young adults.
Bučar Pajek M, Peček Čuk M, Pajek J.
19 November 2011
Category:
Physical Activity
Doi:
Abstract
Background
Research of low back pain (LBP)
has been recently directed towards the younger
age groups due to high predictive value for later
life. The aim of the study was to assess the prevalence and risk factors for LBP in the Slovene population of young adults, which are yet unknown.
Methods
In ...
Severe peritonitis in patients treated with peritoneal dialysis: a case series study
Pajek J, Guček A, Skoberne A, Pintar T
29 May 2011
Category:
Nephrology And Internal Medicine
Doi:
Abstract
Severe peritonitis causing death and/or technique termination (catheter explanted) is one of the most devastating complications of peritoneal dialysis (PD). The aim of this case series study was to reveal the predictors of risk and clinical characteristics of these cases. We included 38 patients wit ...
Treatment of anemia with epoetin in kidney transplant recipients
Bren A, Arnol M, Kandus A, Varl J, Oblak M, Lindič J, Pajek J, Knap B, Kovač D, Mlinšek G, Buturović-Ponikvar J
29 May 2011
Category:
Nephrology And Internal Medicine
Doi:
Abstract
The aim of this study was to analyze the prevalence and efficacy of renal anemia treated with epoetin in maintenance kidney transplant recipients in Slovenia. By the end of 2009, 107 out of 537 patients (19.9%) had been treated with epoetin. A cohort of 49 patients (45.8%) were analyzed in detail: 1 ...
Cardiorenal syndrome: definition, classification and recent results of studies on pathogenesis
Pajek J
31 May 2010
Category:
Nephrology And Internal Medicine
Doi:
Abstract
Background: The term cardiorenal syndrome (CRS) has been used without a consistent definition. Since there is a high clinical impact of heart and kidney disease interactions a unified definition of CRS is warranted. Methods: CRS definition and classification proposal by an international group of aut ...