Articles
Cell-free DNA in the peritoneal effluent of peritoneal dialysis solutions
Pajek J, Kveder R, Gucek A, Skoberne A, Bren A, Bucar M, Cerne D, Lukac-Bajalo J
11 February 2010
Category:
Nephrology And Internal Medicine
Doi:
Abstract
The beneficial effects of novel peritoneal dialysis solutions low in glucose degradation products regarding peritoneal cell apoptosis and necrosis are well established in vitro, however in vivo data is lacking. Cell‐free DNA quantification is a possible method to determine cell damage through apopto ...
Encapsulating peritoneal sclerosis in patients on peritoneal dialysis in Slovenia
Lindic J, Rupnik AT, Tomazic J, Skoberne A, Gucek A, Ferluga D, Pintar T, Ales A, Kovac D, Kveder R, Pajek J, Savicki-Ponikvar B, Bren A
30 July 2009
Category:
Nephrology And Internal Medicine
Doi:
Abstract
Encapsulating peritoneal sclerosis (EPS) is a rare complication in patients on peritoneal dialysis (PD), the prevalence of which increases with the time spent on PD. Various causative factors have been proposed, but the pathogenesis still remains unclear. The aim of our retrospective study was to an ...
Short-term effects of bicarbonate/lactate-buffered and conventional lactate-buffered dialysis solutions on peritoneal ultrafiltration: a comparative crossover study
Pajek J, Kveder R, Bren A, Gucek A, Bucar M, Skoberne A, Waniewski J, Lindholm B
30 April 2009
Category:
Nephrology And Internal Medicine
Doi:
Abstract
Background
This study was designed to compare the effects of a conventional lactate-based peritoneal dialysis (PD) solution (D) and a new biocompatible bicarbonate/lactate-based solution with a low concentration of glucose degradation products (P) on peritoneal ultrafiltration (UF) and other perito ...
Impact of dialysis duration and glucose absorption on nutritional indices in stable continuous ambulatory peritoneal dialysis patients
Pajek J, Gucek A, Kveder R, Bucar-Pajek M, Kaplan-Pavlovcic S, Bren AF.
31 October 2008
Category:
Nutrition
Doi:
Abstract
Objective
The presence of comorbidity is a risk factor for both poor nutrition and poor outcome in continuous ambulatory peritoneal dialysis (CAPD) patients. In CAPD specifically, peritoneal glucose load is associated with a possible suppression of appetite, contributing to protein malnutrition. Thi ...
Short-Term Effects of a New Bicarbonate/Lactate-Buffered and Conventional Peritoneal Dialysis Fluid on Peritoneal and Systemic Inflammation in CAPD Patients: A Randomized Controlled Study
Pajek J, Kveder R, Bren A, Gucek A, Ihan A, Osredkar J, Lindholm B
31 December 2007
Category:
Nephrology And Internal Medicine
Doi:
Abstract
Objectives
This study was designed to compare the local peritoneal and systemic inflammatory effects of a conventional lactate-based (Lac) peritoneal dialysis (PD) solution and a new biocompatible bicarbonate/lactate-based (Bic/ Lac) solution having low concentration of glucose degradation products ...
Epoetin Responsiveness in Peritoneal Dialysis Patients: A Multi‐center Slovenian Study
Pajek J, Bucar-Pajek M, Grego K, Gucek A, Bevc S, Ekart R, Vujkovac B, Golob-Kosmina P, Kandus A, Bren AF
20 June 2005
Category:
Nephrology And Internal Medicine
Doi:
Abstract
The objective of our study was to assess the influence of residual renal function and other factors on epoetin requirements in chronic peritoneal dialysis patients. Fifty‐one stable patients (mean age ± SD: 52 ± 13 years; 20 women) without recent bleeding, bone marrow disease or malignancy were recr ...
Follow-up of Kidney Graft Recipients With Cyclosporine-Associated Hemolytic-Uremic Syndrome and Thrombotic Microangiopathy
Bren A, Pajek J, Grego K, Buturovic J, Ponikvar R, Lindic J, Knap B, Vizjak A, Ferluga D, Kandus A
23 May 2005
Category:
Nephrology And Internal Medicine
Doi:
Abstract
The study was based on 462 patients who underwent kidney transplantation from 1986 through 2004. Cyclosporine (CsA)-related thrombotic microangiopathy (TMA) was observed in 15 (3.3%) patients. The donor ages ranged from 9 to 51 years and cold ischemia times from 12 to 31 hours. Hemolytic-uremic synd ...
Experimental and clinical significance of renal functional reserve determination
Pajek J, Kaplan-Pavlovčič S
7 July 2002
Category:
Nephrology And Internal Medicine
Doi:
Abstract
Background. Renal functional reserve (RFR) is defined as the temporary increase in glomerular filtration rate (GFR) which follows the ingestion of proteins or infusion of aminoacids. This renal vasodilatatory response is probably mediated by several mechanisms, with nitric oxide being one of the mos ...